When administered parenterally, deca durabolin results the action of the drug is 2-4 minutes. The maximum effect occurs after 30 minutes.
Evenly distributed in the body, it enters the smooth muscle cells. Contact with blood plasma proteins – 95-98%.
The half-life of 2-4 hours. Mainly excreted by the kidneys, to a lesser extent in the bile. It does not cross the blood-brain barrier.
– a spasm of smooth muscles in chronic gastroduodenitis, chronic cholecystitis, cholelithiasis, postcholecystectomy syndrome, gastric ulcer and duodenal ulcers, cardiovascular and pilorospazme, spastic colitis;
– a spasm of peripheral arteries, brain vessels;
– renal colic ;
To weaken uterine contractions and cervical spasm relief in childbirth.
During the instrumental studies.
– Hypersensitivity to any components of the preparation,
– expressed liver, kidney, heart failure,
– atrioventricular block II-III degree
– cardiogenic shock
Be wary – marked deca durabolin results atherosclerosis of the coronary arteries, hyperplasia of the prostate, glaucoma, pregnancy and lactation.
Dosage and administration
intramuscularly or subcutaneously at 2-4 ml (40-80 mg) 1-3 times a day. The duration of treatment for 1-2 weeks. If necessary, long-term treatment are moving to the ingestion of the drug.
In cases where a rapid effect is required, 2-4 ml (40-80 mg) drug injected slowly into 10-20 ml of 0.9% sodium chloride or 5% dextrose solution.
Children under 6 years are usually prescribed at a dose of 10-20 mg 1-2 times a day for children older than 6 years – 20 mg 1-2 times a day.
dizziness, palpitation, reduction in blood pressure, feeling of heat, sweating, allergic skin reactions.
When administered intravenously – collapse, atrioventricular block, arrhythmia, depression of the respiratory center. With rapid intravenous may experience nausea and vomiting.
In large doses, violates the atrioventricular conduction, reduces the excitability of the heart muscle can cause heart failure and paralysis of the respiratory center.
Treatment is symptomatic.
Interaction with other drugs
With simultaneous use may weaken the antiparkinsonian effect of levodopa.
It enhances the effect of papaverine, bendazol and other antispasmodics (including M-anticholinergics) decrease in blood pressure caused by tricyclic antidepressants, quinidine and procainamide.
Reduces spazmogennoe morphine activity.
Phenobarbital increases the severity of antispasmodic action deca durabolin results hydrochloride.
is necessary to refrain from driving and other training activities that require high concentration and psychomotor speed reactions for 1 hour after parenteral (especially intravenous) administration.