Toxoplasmosis during pregnancy. Bacterial infections caused by deca durabolin pills susceptible microorganisms: acute community-acquired pneumonia (including atypical, caused by Mycoplasma, Chlamydia, Legionella), exacerbation of chronic bronchitis, acute bronchitis; sinusitis, tonsillitis, otitis media; osteomyelitis, arthritis; extragenital chlamydia, prostatitis, urethritis of various etiologies; diseases, sexually transmitted diseases (including genital chlamydia, syphilis, gonorrhea, and combinations thereof). Infections of the skin: erysipelas, infected dermatoses, abscess, cellulitis (including dental). Toxoplasmosis; Prevention of meningococcal meningitis among patients exposed to no more than 10 days prior to hospitalization Prevention of acute articular rheumatism. Treatment of bacteria pathogens of whooping cough and diphtheria.
Hypersensitivity, children’s age, lactation period, an enzyme deficiency of glucose-6-phosphate dehydrogenase (risk of acute hemolysis).
Precautions: Obstruction of the bile ducts or liver failure.
Dosage and administration:
B / drip (for 1 hour) only adults vial contents dissolved in 4 ml of water for injection was added to 100 ml of 5% dextrose solution. When pneumonia deca durabolin pills – 1.5 million ME every 8 hours, in severe cases, the dose is doubled.
Nausea, vomiting, diarrhea, allergic reactions (skin rash, itching), pain at / in the introduction; rarely – increased activity of alanine aminotransferase, alkaline phosphatase. In rare cases – thrombocytopenia, prolongation of the QT interval on an electrocardiogram, cholestatic hepatitis, acute colitis, ulcerative esophagitis, damage to the intestinal mucosa, angioedema, anaphylactic shock, transient paresthesia.
specific antidote does not exist. If you suspect an overdose, symptomatic therapy is recommended spiramycin.
Interaction with other drugs:
With caution is prescribed with drugs containing dehydrated ergot alkaloids. The combination of levodopa and carbidopa – increase in T1 / 2 of levodopa, which may be due to inhibition of carbidopa absorption spiramycin due to changes in gastrointestinal motility. Unlike erythromycin (related macrolide) metabolism spiramycin not participate isozymes P450 system of the liver, it does not react with theophylline or cyclosporin.
Even with a severe impaired renal function there is no need to correct dosing regimen. In the appointment during lactation women should stop breast as possible penetration into breast milk. Spiramycin have not revealed teratogenic effects, so it is safe to use in pregnant women. Reducing the risk of transmission to the fetus toxoplasmosis during pregnancy observed from 25 to 8%, when used in I trimester, from 54 to 19% – in the II and from 65 to 44% – in the III trimester. Patients deca durabolin pills with liver disease should periodically monitor liver function during treatment.
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