When oral absorption – high, poluabsorbtsii period – 12 min. Bioavailability – 100%. Evenly distributed in the body, it enters the smooth muscle cells. Deca durabolin for salen with the plasma protein -. 95-98%. Mainly excreted by the kidneys, to a lesser extent – in the bile. It does not cross the blood-brain barrier.
Prevention and treatment of functional states, and pain associated with spasm of smooth muscles in chronic gastroduodenitis, chronic holitsistit, cholelithiasis, postcholecystectomy syndrome, gastric ulcer and 12 duodenal ulcer, cardiovascular and pilorospazme, spastic colitis. Applied also spasm of peripheral arteries, brain blood vessels, kidney stones, algodismenorree, to weaken uterine contractions and cervical spasm relief in childbirth, during the instrumental studies.
: Hypersensitivity to the drug. Severe hepatic, renal, cardiac failure; AV-block II-III degree, cardiogenic shock, hypotension.
Dosing and Administration
Adults appoint inside on 40-80 mg 2-3 times a day. Children under 6 years are administered in a single dose of 10-20 mg, from 6 to 12 years – 20 mg 1-2 times a day.
Dizziness, palpitations, hypotension, sensation of heat, sweating, allergic skin reactions.
In large doses, violates deca durabolin for sale the atrioventricular conduction, reduces the excitability of the heart muscle can cause heart failure and paralysis of the respiratory center.
With care prescribe a drug to patients with severe coronary atherosclerosis, enlarged prostate, glaucoma, during pregnancy and lactation.
Interaction with other drugs
With simultaneous use may weaken the anti-Parkinsonian effect of levodopa.
Enhances the effect of papaverine, bendazol and other antispasmodics (including M-anticholinergics), hypotension caused by tricyclic antidepressants, quinidine and procainamide.
Reduces deca durabolin for sale spazmogennoe morphine activity.
Phenobarbital increases severity antispasmodic action Spazoverina.